Located in the heart of the San Juan Metropolitan Area, the Knowledge Corridor project presented an economic development initiative to connect existing and proposed uses of higher education, R&D, medical institutions, and biotechnology in the existing urban tissue of the Tren Urbano mass-transit corridor. The former state prison 70-acre site known as Oso Blanco in Rio Piedras, almost at the geographical center of the Knowledge Corridor, became the focus for the development of the Science City Master Plan for the long-term development mixed use community with a rich R&D center.